The game went to extra-time and penalties as another Pompey opener was cancelled out by the U’s – this time Marcus Harness’ fine first-half strike which was levelled by a Ellis Harrison own goal on the stroke of half-time – to leave the game 2-2 on aggregate.
Little separated the two teams on penalties either, until Cameron McGeehan’s effort was saved by former Blues keeper Simon Eastwood.
That allowed the hosts to take advantage of the miss, with Cameron Brannagan doing just that with the last penalty of the shootout to give Oxford a 5-4 win.